Nature methods
Inferring cell differentiation maps from lineage tracing data.
Palash Sashittal, Richard Y Zhang, Benjamin K Law, Henri Schmidt, Alexander Strzalkowski, Adriano Bolondi, Michelle M Chan, Benjamin J Raphael
Published: 202510.1038/s41592-025-02903-z
Abstract
During development, cells differentiate through a hierarchy of increasingly restricted cell types, a process that is summarized by a cell differentiation map. Recent technologies profile lineages and cell types at scale, but existing methods to infer…
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