Nature immunology
A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.
Saumya Kumar, Chaofan Li, Liang Zhou, Qiuyao Zhan, Ahmed Alaswad, Sonja Volland, Bibiana Costa, Simon Alexander Krooss, Isabel Klefenz, Hagen Schmaus, Antonia Zeuzem, Dorothee von Witzendorff, Helena Lickei, Lea Pueschel, Anke R M Kraft
Published: 202610.1038/s41590-025-02387-1
Abstract
The mechanisms driving immune dysregulation in long COVID disease remain elusive. Here we integrated single-cell multiome data, immunological profiling and functional assays to investigate immune alterations across multiple cohorts. A transcriptional…
Preview only. Read the full abstract at the source