Nature genetics
The predicament of heritable confounders.
Na Cai, Andy Dahl, Richard Border, Aditya Gorla, Jolien Rietkerk, Joel Mefford, Noah Zaitlen, Morten Dybdahl Krebs, Andrew J Schork, Kenneth Kendler, Jonathan Flint
Published: 202610.1038/s41588-025-02465-y
Abstract
Identifying significant associations between genetic loci and psychiatric disorders is dependent on very large sample sizes. Methods for diagnosing diseases on this scale, such as the use of self-assessment questionnaires and data from electronic hea…
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