Nature biotechnology
Predicting small molecule-RNA interactions without RNA tertiary structures.
Yuhan Fei, Pengfei Wang, Jiasheng Zhang, Xinyue Shan, Zilin Cai, Jianbo Ma, Yangming Wang, Qiangfeng Cliff Zhang
Published: 202610.1038/s41587-025-02942-z
Abstract
Small molecules can bind RNAs to regulate their fate and functions, providing promising opportunities for treating human diseases. However, current tools for predicting small molecule-RNA interactions (SRIs) require prior knowledge of RNA tertiary st…
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