Nature biotechnology
Programmable initiation of mRNA translation by trans-RNA.
Longfei Jia, Tan-Trung Nguyen, Saori Uematsu, Yifei Gu, Shengcho Shi, Yaser Hashem, Shu-Bing Qian
Published: 202510.1038/s41587-025-02897-1
Abstract
Several approaches exist to silence genes, but few tools are available to activate individual mRNAs for translation inside cells. Guiding ribosomes to specific start codons without altering the original sequence remains a formidable task. Here we des…
Preview only. Read the full abstract at the source