Nature
Pre-assembly of biomolecular condensate seeds drives RSV replication.
Dhanushika Ratnayake, Marie Galloux, Sanne Boersma, Marko Noerenberg, Christina Sizun, Carlos Sacristan, Julien Sourimant, Anke J Lakerveld, Anne T Gelderloos, Leonie Apperloo, Yana Demyanenko, Matthijs J D Baars, Rupa Banerjee, Birgit Dreier, Sven Furler
Published: 202610.1038/s41586-025-10071-5
Abstract
During infection, many RNA viruses, including respiratory syncytial virus (RSV), form specialized biomolecular condensates, viral factories (VFs), where viral transcription and replication occur1,2. Paradoxically, high protein concentrations are typi…
Preview only. Read the full abstract at the source