Nature
Neuro-epithelial circuits promote sensory convergence and intestinal immunity.
Wen Zhang, Elizabeth R Emanuel, Hiroshi Yano, Jazib Uddin, Stephen Gaudino, Zili Xie, Hiroshi Ichise, Zhen Wang, Maureen N Cowan, Mengze Lyu, Xiaoxiao Hou, Peng Zeng, Elin Hu, Victoria Ribeiro de Godoy, Alex Grier
Published: 202610.1038/s41586-025-09921-z
Abstract
Type 2 inflammation at barrier surfaces is an evolutionarily conserved response that promotes immunity to helminth parasites, allergic inflammation and tissue repair1-4. Direct sensing of environmental triggers by epithelial cells initiates type 2 in…
Preview only. Read the full abstract at the source