Nature reviews. Clinical oncologyHumansTumor MicroenvironmentPancreatic NeoplasmsCarcinomaPancreatic Ductal
The tumour microenvironment in pancreatic cancer - new clinical challenges, but more opportunities.
Heng-Chung Kung, Kevin W Zheng, Jacquelyn W Zimmerman, Lei Zheng
Published: 202510.1038/s41571-025-01077-z
Abstract
Patients with advanced-stage pancreatic ductal adenocarcinoma (PDAC) predominantly receive chemotherapy, and despite initial responses in some patients, most will have disease progression and often dismal outcomes. This lack of clinical effectiveness…
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