Nature reviews. Cancer
Opportunities and challenges of targeting cGAS-STING in cancer.
Changzheng Lu, Wenyan Wang, Yang-Xin Fu
Published: 202610.1038/s41568-025-00894-9
Abstract
The cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)-stimulator of interferon genes (STING) pathway has a crucial role in detecting tumour-derived DNA, whether the pathway is generated spontaneously or induced therapeutically. A…
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