Nature nanotechnology
Engineered mucus-tethering bispecific nanobodies enhance mucosal immunity against respiratory pathogens.
Liming Zhao, Kyle L O'Donnell, Megha Dubey, Yuting Wang, Nathan R Martinez, Yunxiao Zhang, Holly M Steininger, Chao Ma, Vamsee Mallajosyula, Lorene L Y Lee, Rovin N Lachmansingh, Suzan Stavitsky, Eri Takematsu, Malachia Y Hoover, Honglin Chen
Published: 202610.1038/s41565-025-02107-8
Abstract
Despite advances in vaccine and antiviral drug development, the prevention of respiratory viral infection and transmission remains a substantial challenge worldwide. One obvious limitation of these approaches is that they do not provide robust protec…
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