Nature nanotechnologyAnimalsArthritisRheumatoidMiceMacrophages
Bioengineered photosynthetic nanothylakoids reshape the inflammatory microenvironment for rheumatoid arthritis therapy.
Ziyue Li, Yipei Yang, Yesi Shi, Dehong Hu, Duyang Gao, Yan Zhang, Hao Yu, Zichao Luo, Qimanguli Saiding, Na Kong, Hongyan Qian, Yuan Liu, Hairong Zheng, Yingjia Li, Wei Tao
Published: 202610.1038/s41565-025-02063-3
Abstract
Reducing individual inflammatory factors does not always translate into clinical efficacy in rheumatoid arthritis (RA), an autoimmune disease characterized by joint inflammation. Proinflammatory M1 macrophages are a key driver of the hyperinflammator…
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