Nature microbiology
Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases.
Brendan Elsworth, Caroline D Keroack, Yasaman Rezvani, Aditya S Paul, Keare A Barazorda, Niel C Bauer, Jacob A Tennessen, Samantha A Sack, Cristina K Moreira, Marc-Jan Gubbels, Marvin J Meyers, Kourosh Zarringhalam, Manoj T Duraisingh
Published: 202610.1038/s41564-025-02238-7
Abstract
Egress from host cells is fundamental for the spread of infection by apicomplexan parasites, including Babesia species. These tick-borne pathogens represent emerging zoonoses, but treatment options are limited. Here, using microscopy, transcriptomics…
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