Nature microbiology
Large-scale testing of antimicrobial lethality at single-cell resolution predicts mycobacterial infection outcomes.
Alexander Jovanovic, Frederick K Bright, Ahmad Sadeghi, Basil Wicki, Santiago E Caño Muñiz, Greta C Giannini, Sara Toprak, Loïc Sauteur, Anna Rodoni, Andreas Wüst, Andréanne Lupien, Sonia Borrell, Dorothy M Grogono, Nicole E Wheeler, Philippe Dehio
Published: 202610.1038/s41564-025-02217-y
Abstract
In vitro antibiotic testing is important for guiding therapy and drug development. Current methods are focused on growth inhibition in bulk bacterial populations but often fail to accurately predict treatment responses. Here we introduce Antimicrobia…
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