Nature microbiologyAnimalsMalaria VaccinesNanoparticlesMicePlasmodium falciparum
A Plasmodium-derived nanoparticle vaccine elicits sterile protection against malaria in mice.
Dashuang Shi, Rui Ma, Richi Gupta, Thayne H Dickey, Palak N Patel, Nichole D Salinas, Wai Kwan Tang, Alaysies Queen, Myesha Singleton, Nida Delbe, Solomon Conteh, Lynn E Lambert, Patrick E Duffy, Niraj H Tolia
Published: 202610.1038/s41564-025-02209-y
Abstract
Protein nanoparticles in infectious disease vaccines enable protection through the periodic arrangement of antigens on their surface. These nanoparticles arise from organisms unrelated to the target disease, limiting their role as presentation platfo…
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