Nature microbiologyAnimalsMiceCandida albicansPhenylethyl AlcoholQuorum Sensing
Interkingdom sensing of fungal tyrosol promotes bacterial antifungal T6SS activity in the murine gut.
Lingfang Zhu, Yuxin Zuo, Rui Cui, Peishuai Fu, Yuqi Liu, Zhuo Wang, Xinquan He, Danyang Yu, Zhiyan Wei, Shuyu Li, Yang Wang, Changfu Li, Yao Wang, De-Feng Li, Shuang-Jiang Liu
Published: 202610.1038/s41564-025-02208-z
Abstract
Type VI secretion systems (T6SSs) are molecular machines used by bacteria to release effectors that target either host cells, competing bacteria or fungi. Regulatory mechanisms underlying antifungal T6SS activity remain unexplored. Here we show, usin…
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