Nature materials
Tumour priming by ultrasound mechanogenetics for CAR T therapy.
Chi Woo Yoon, Chunyang Song, Dung Ngo Minh Nguyen, Xi Yu, Linshan Zhu, Phuong Ho, Ziliang Huang, Gengxi Lu, Yuxuan Wang, Fan Wei, Yunjia Qu, Ali Zamat, Alexa Lewis, Ruimin Chen, Yushun Zeng
Published: 202510.1038/s41563-025-02391-8
Abstract
Cell-based cancer immunotherapy holds potential as a therapeutic approach, yet its application for solid tumour treatment remains challenging. Here we report a focused-ultrasound-based approach that mechanically induces the localized expression of CD…
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