Nature biomedical engineering
Engineered thoracic spinal cord organoids for transplantation after spinal cord injury.
Yanjing Zhu, Ruiqi Huang, Liqun Yu, Zhibo Liu, Yuchen Liu, Wenyong Fan, Gufa Lin, Zhaojie Wang, Xiaolie He, Xu Xu, Bei Ma, Youwei Chen, Yuxin Bai, Jing Li, Bairu Chen
Published: 202510.1038/s41551-025-01549-8
Abstract
Stem-cell-based neural tissue engineering and spinal cord organoids show promises for spinal cord injury repair. However, the native spinal cord presents cell heterogeneity and a stereotypical spatial structure that makes difficult their recapitulati…
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