Nature biomedical engineering
Systematic production of human kidney organoids for transplantation in porcine kidneys during ex vivo machine perfusion.
Elena Garreta, Daniel Moya-Rull, Alberto Centeno, Andrés Marco, Asier Ullate-Agote, Gaia Amato, Carlos J Aranda, Roger Oria, Daniel Lozano-Ojalvo, Merel B F Pool, Tim L Hamelink, Idoia Lucía Selfa, Federico González, Carolina Tarantino, Alejandro Montero Salinas
Published: 202510.1038/s41551-025-01542-1
Abstract
Organoids derived from human pluripotent stem (hPS) cells hold promise for therapeutic purposes. However, technological advances to overcome their massive production while ensuring differentiation fidelity are still lacking. Here we report a procedur…
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