NPJ vaccines
Live-attenuated foot-and-mouth disease virus vaccine engineered by codon deoptimization induces a strong protective immune response in cattle.
Sarah E Attreed, Christina Silva, Monica Rodriguez-Calzada, Ryan D Heimroth, Michael Oldakowski, Carolina Stenfeldt, Paul Azzinaro, Edward Spinard, Aishwarya Mogulothu, Steffen Mueller, Bruce Taillon, Jonathan Arzt, Elizabeth Rieder, Teresa de Los Santos, Fayna Díaz-San Segundo
Published: 202610.1038/s41541-025-01368-7
Abstract
Foot-and-mouth disease (FMD) is a fast-spreading, economically devastating veterinary viral disease. While inactivated vaccines have contributed to FMD control worldwide, recent outbreaks in Europe and Asia highlight the need for new control strategi…
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