NPJ systems biology and applications
Modeling the microRNA regulation of TGF-β/SMAD signaling pathways for seizure control in temporal lobe epilepsy.
Kurt J A Pumares, Daniel P Martins, Aiman Khalil, Jochen H M Prehn, Deirdre Kilbane
Published: 202610.1038/s41540-025-00643-6
Abstract
Temporal lobe epilepsy (TLE) is the most prevalent type of focal epilepsy. Recent developments in sequencing, proteomics and network analysis tools provide new avenues for investigating potential molecular therapeutic targets. Both the TGF-β/SMAD sig…
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