npj aging
Frailty-related plasma metabolomic signatures predict long-term mortality risk and implicate systemic aging pathways: evidence from a prospective cohort study.
Xiru Zhang, Xin Feng, Wenchao Liu, Ruiyan Liu, Qingmei Huang, Peidong Zhang, Zhihao Li, Xifeng Li, Chen Mao, Chuanzhi Duan
Published: 202610.1038/s41514-025-00327-9
Abstract
Frailty is a common geriatric syndrome associated with increased mortality, yet its underlying biological mechanisms and potential value for early risk stratification remain inadequately understood. In this large prospective cohort of more than 260,0…
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