Nature communications
Granzyme B-mimetic nanozyme for nanovesicle targeted anticancer applications.
Xueyan Hu, Qiqi Liu, Helong Kang, Ming Zhao, Zheng Zhou, Yuanke Li, Weicheng Peng, Tianyi Qi, Ruming Liu, Li Jiao, Jie Zhuang, Yijin Liu, Stephen Mann, Xinglu Huang
Published: 202610.1038/s41467-026-68773-x
Abstract
Cytotoxic T lymphocytes play a crucial role in anti-tumour immunity, with granzyme B (GrB) being a decisive factor in this process. Developing a GrB-based delivery system to mimic T cell-based immunotherapy holds promise but remains challenging. Here…
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