Nature communications
Modulation of Nudt21 levels reveals dose-dependent roles of alternative polyadenylation in tissue regeneration.
Nikolaos Tsopoulidis, Masaki Yagi, Justin Brumbaugh, Shinya Ito, Víctor López-Soriano, Robert Morris, Yoseop Yoon, Kathleen A Messemer, Kuan-Hung Lin, Eric F Zaniewski, Rebecca Gorelov, Aaron J Huebner, Amy J Wagers, Hanno Hock, Günter Kramer
Published: 202610.1038/s41467-026-68630-x
Abstract
Stem cells continually self-renew and differentiate to sustain tissue homeostasis, yet the role of post-transcriptional mechanisms in guiding these processes remains incompletely understood. Here, we demonstrate that the regulation of 3'UTR length vi…
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