Nature communications
Bionic Janus hydrogel drives infected Achilles tendon regeneration via mechano-immune spatiotemporal steering.
Jie Li, Zishuo Wang, Wenjing Yang, Yuchen Zhang, Yanjun Wang, Xuhui Wang, Hongrui Wang, Yang Xie, Shuogui Xu, Yan Shang, Chunyu Xue, Yuntong Zhang, Shuo Fang
Published: 202610.1038/s41467-026-68514-0
Abstract
The healing of infected tendons is hindered by mechanical dysfunction, tissue adhesion, bacterial colonization, and immune imbalance. Inspired by the biphasic "adhesion-lubrication" structure of tendon sheaths, we developed a Janus hydrogel, named HA…
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