Nature communicationsKidney TransplantationAnimalsHumansGraft RejectionEpithelial Cells
Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection.
Anna Maria Pfefferkorn, Lorenz Jahn, Patrick T Gauthier, Vera Anna Kulow, Johannes Roeles, Niklas Müller-Bötticher, Louisa M S Gerhardt, Janna Leiz, Sadia Sarfraz, Izabela Plumbom, Robert Greite, Svjetlana Lovric, Jaba Gamrekelashvili, Florian Limbourg, Jessica Schmitz
Published: 202610.1038/s41467-026-68397-1
Abstract
T-cell-mediated rejection (TCMR) remains a major cause of kidney transplant failure, despite being considered treatable. Its impact reflects a limited understanding of the underlying molecular mechanisms and their clinical consequences. To address th…
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