Nature communications
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Haoyi Chen, Li Wei, Qiang Yu, Chenxi Wang, Huizhen Fan, Ming Li, Ruonan Dong, Yingying Ma, Jiahao Jiang, Lianfu Deng, Mei X Wu, Min Lu
Published: 202610.1038/s41467-026-68318-2
Abstract
Osteomyelitis, especially multidrug-resistant cases, remains a formidable clinical challenge due to recurrent infections and antibiotic limitations. Here, we present an injectable GaCuVan&HACHO-BSA hydrogel that self-assembles in situ within the bone…
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