Nature communications
Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy.
Bao Loc Nguyen, Ngoc Duy Le, Thi Oanh Oanh Nguyen, Daehyeon Ahn, Basavaraj Rudragouda Patil, Beomsu Kim, Cao Dai Phung, Duc-Vinh Pham, Jung Min Lee, Jiwoo Hong, Jae-Hoon Chang, Sae Kwang Ku, Jeonghwan Kim, Jong Oh Kim
Published: 202610.1038/s41467-025-68279-y
Abstract
Although disruptions in metal ion homeostasis leading to severe cellular damage and regulated cell death are a promising strategy for cancer immunotherapy, challenges in overloading these ions to tumor cells without premature release have limited the…
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