Nature communications
AKAP95 condensates regulate transcription and can be targeted in MLL-fusion driven oncogenesis.
Xiang Yan, Yongkun Luan, Yi Zhu, You Cai, Fanghua Ye, Liangchun Yang, Kaibo Zhu, Jing Hu, Shuangzi Luo, Jiazheng Lin, Yixiu Wang, Yulu Huang, Ping Sun, Zhenhua Yang, Bi Shi
Published: 202610.1038/s41467-025-68192-4
Abstract
RNA binding proteins could regulate transcription through modulating RNA polymerase II involved transcriptional condensates with the aid of nascent RNA. However, whether this mechanism also contributes to tumorigenesis is still unknown. Here, we show…
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