Nature communications
High-fat diet disrupts a septal control on feeding to promote obesity in male mice.
Shaolei Jiang, Shishi Lai, Haiyang Jing, Xiaocong Wu, Fengling Li, Bo Chen, Jin Bao, Liping Wang, Gaowei Chen, Yingjie Zhu
Published: 202510.1038/s41467-025-68010-x
Abstract
The global epidemic of diet-induced obesity poses a significant health challenge. Among brain regions regulating energy homeostasis, the lateral septum has emerged as a critical brake on feeding behavior to prevent overeating. However, the neural ada…
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