Nature communications
Computational design of dynamic biosensors for emerging synthetic opioids.
Alison C Leonard, Chase Lenert-Mondou, Rachel Chayer, Samuel Swift, Zachary T Baumer, Ryan Delaney, Anika J Friedman, Nicholas R Robertson, Norman Seder, Jordan Wells, Lindsey M Whitmore, Sean R Cutler, Michael R Shirts, Ian Wheeldon, Timothy A Whitehead
Published: 202610.1038/s41467-025-67994-w
Abstract
Nitazenes are an emergent class of synthetic opioids that often rival or exceed fentanyl in their potency. These compounds have been detected internationally in illicit drugs and are the cause of increasing numbers of hospitalizations and overdoses.…
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