Nature communicationsHumansProteomicsProteomeClinical Decision-MakingMass Spectrometry
An adaptive, continuous-learning framework for clinical decision-making from proteome-wide biofluid data.
Johannes B Müller-Reif, Vincent Albrecht, Vincenth Brennsteiner, Jakob M Bader, Peter V Treit, Nicolai J Wewer Albrechtsen, Susanne Pangratz-Führer, Matthias Mann
Published: 202610.1038/s41467-025-67968-y
Abstract
Mass spectrometry (MS)-based proteomics provides deep molecular insights from patient samples, but clinical use has been limited by missing values, static biomarker panels, and the need for targeted assay development. We present a framework - Adaptiv…
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