Nature communicationsAnimalsVagus Nerve StimulationVagus NerveSwineMotor Neurons
Application of kilohertz-frequency block to mitigate off-target motor effects of vagus nerve stimulation in swine.
Kevin P Cheng, Ashlesha Deshmukh, Aaron K Gholston, Megan L Settell, Bruce E Knudsen, Maria LaLuzerne, James K Trevathan, Aaron J Suminski, Nicole A Pelot, Warren M Grill, Kip A Ludwig
Published: 202510.1038/s41467-025-67823-0
Abstract
Selective activation of small versus large diameter nerve fibers represents a broad challenge in the electrical modulation of neural activity for clinical applications. For example, off-target activation of motor nerve fibers was implicated in severa…
Preview only. Read the full abstract at the source