Genes and immunity
Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury.
Yulin Wang, Cheng Zhu, Shiqi Lv, Xinhui Huang, Jiayi Wang, Shuangxin Yuan, Yue Yang, Xiaoqiang Ding, Ziyan Shen, Xiaoyan Zhang
Published: 202510.1038/s41435-025-00364-0
Abstract
Acute kidney injury (AKI) is a common and critical clinical condition with complex pathogenesis and limited early intervention options. Ferroptosis, an iron-dependent form of cell death driven by lipid peroxidation, plays a pivotal role in AKI develo…
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