Gene therapy
Evaluation of methods to increase the expression of cytokine-induced killer cell chemoattractant cytokines in pancreatic cancer.
Maria Bunuales, Susana Inoges, Ascension Lopez-Diaz de Cerio, Sandra Hervas-Stubbs, Javier Rodriguez, Manuela Gonzalez-Aparicio, Patricia Jauregui, Ruben Hernandez-Alcoceba
Published: 202610.1038/s41434-025-00590-1
Abstract
Adoptive Cell Therapies based on cytokine-induced killer cells (CIKs) can address the heterogeneity of solid tumors due to their multiple mechanisms of cancer cell recognition. However, tumor trafficking is one of the main limitations. In this work,…
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