Cell death discovery
Modeling hepatocellular carcinoma and its microenvironment on a chip.
Orsola Mocellin, Stéphane Treillard, Abbie Robinson, Aleksandra Olczyk, Thomas Olivier, Chee P Ng, Arthur Stok, Gilles van Tienderen, Monique M A Verstegen, Jeroen Heijmans, Dorota Kurek, Sebastian J Trietsch, Henriëtte L Lanz, Paul Vulto, Jos Joore
Published: 202510.1038/s41420-025-02917-8
Abstract
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Its incidence is increasing and is closely related to advanced liver disease. Interactions in the HCC microenvironment between tumor cells and the associated stroma actively regu…
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