Cell death & disease
Targeting GNG4 inhibits tumor progression and restores enzalutamide sensitivity in prostate cancer by suppressing autophagy.
Lei Chen, Jingyan Zhang, Yanshuo Hu, Xufeng Peng, Hong Wang, Binghua Chen, Jun Xia, Wei Xue, Chun-Wu Pan
Published: 202610.1038/s41419-026-08421-w
Abstract
Prostate cancer (PCa) is the most prevalent malignancy among men worldwide. Advanced prostate cancer is characterized by aggressive progression, limited therapeutic response, and poor prognosis. Elucidating its oncogenic mechanisms may provide new op…
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