Cell death & diseaseGlioblastomaHumansHomeodomain ProteinsLow Density Lipoprotein Receptor-Related Protein-6Wnt Signaling Pathway
IRX3-CDK14 axis promotes glioblastoma progression by regulating LRP6-mediated canonical Wnt/β-catenin pathway.
Yongjia Gao, Guanghui Zhang, Yahui Yu, Jie Gao, Songtao Ren, Xiaonan Wei, Rui Yang
Published: 202510.1038/s41419-025-08387-1
Abstract
Iroquois Homeobox 3 (IRX3), a highly conserved member of the Iroquois homeobox gene family, has been implicated in obesity through its regulation of fat mass and obesity-associated (FTO) gene. Emerging evidence indicates that IRX3 plays critical role…
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