Cell death and differentiation
P4HA3 drives cervical cancer lymphatic metastasis by facilitating ACLY-mediated ferroptosis resistance.
Li Yuan, Hongye Jiang, Meng Xia, Weijia Wen, Haolin Fan, Songlin Liu, Yuandong Liao, Pan Liu, Yan Jia, Xueyuan Zhao, Linna Chen, Caixia Shao, Yan Liao, Dingze Xu, Tianyu Liu
Published: 202510.1038/s41418-025-01644-y
Abstract
The lymph node is the most common site of distant metastasis of cervical cancer (CCa), which elicits dismal prognosis and limited efficiency for treatment. Identification of the factors contributing to CCa lymphatic metastasis is needed to develop ef…
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