Cancer gene therapy
Pleiotropic effects of all-trans retinoic acid in attenuating the hallmarks of colorectal cancer- challenges and scope of differentiation therapy.
Antony Anista Michael, Pavithra Balakrishnan, Priyadharshini Tamizhmani, Kishore Thirunavukarasu, Selvakumar Subramaniam, Thirunavukkarasu Velusamy
Published: 202510.1038/s41417-025-00996-4
Abstract
Colorectal Cancer (CRC) is a heterogenous malignancy, attributed by a vast array of mutations that govern the adenoma-carcinoma sequence. The underlying molecular mechanism of CRC recurrence is diverse and complex, in which cancer stem cells (CSCs) r…
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