British journal of cancer
Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples.
Markus Ball, Susanne Beck, Darius Wlochowitz, Tina Fuchs, Katja Lorenz, Christiane Zgorzelski, Alejandro Pallares Robles, Michael Allgäuer, Anna-Lena Volckmar, Hannah Goldschmid, Iordanis Ourailidis, Regine Brandt, Petros Christopoulos, Michael Thomas, Huriye Seker-Cin
Published: 202610.1038/s41416-025-03307-8
Abstract
BACKGROUND: Whole Transcriptome Sequencing (WTS) is a comprehensive alternative to targeted panels for detecting gene fusions and splice variants. To integrate WTS into clinical diagnostics, we compared its performance against established fusion assa…
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