British journal of cancerHumansNeuropeptide YMouth NeoplasmsReceptorsAnimals
Crosstalk of NPY and TGFβ orchestrates the signaling to facilitate perineural invasion of oral squamous cell carcinoma.
Jing Bi, Ketong Liu, Yiru Luo, Yueqi Zhou, Zhengyan Liu, Junting Tao, Jinhui Wei, Marene Landstrom, Yabing Mu, Guangxiang Zang
Published: 202610.1038/s41416-025-03261-5
Abstract
BACKGROUND: Perineural invasion (PNI) frequently occurs in oral squamous cell carcinoma (OSCC) and predicts poor prognosis. Although PNI is increasingly recognised as a process driven by tumour-nerve crosstalk, the underlying molecular mechanisms rem…
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