British journal of cancer
ULK1 promotes oxaliplatin resistance of colon cancer via phosphorylation of Bax S184.
Ze Rong, Jing Xing, Liangpei Wu, Kaifeng Zheng, Linrong Pang, Jun Chen, Xiaofeng Jin
Published: 202610.1038/s41416-025-03223-x
Abstract
BACKGROUND: Oxaliplatin resistance continues to undermine therapeutic outcomes in colon cancer (CC). Recent investigations point to unc-51 like kinase 1 (ULK1)-mediated disruption of apoptotic pathways as a potential driver of chemoresistance, though…
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