Acta pharmacologica Sinica
Protopanaxatriol restores cognitive function in okadaic acid-treated mice via direct inhibition of pathological CDK5 activity.
Ye Peng, Sha-Sha Wang, Ke-Dao Lai, Jun-Rui Ye, Wen-Bing He, Xu Yan, Zhao Zhang, Shi-Feng Chu, Nai-Hong Chen
Published: 202610.1038/s41401-025-01709-1
Abstract
Alzheimer's disease (AD), a prevalent neurodegenerative dementia, presents therapeutic challenges due to safety concerns about amyloid-targeting strategies. Traditional Chinese medicine (TCM) may offer alternative avenues for exploration. Ginsenoside…
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