Acta pharmacologica Sinica
β-Hydroxybutyrate improves glymphatic system function and alleviates cerebral edema in mice after ischemic stroke.
Ming-Jia Yu, Rui-Qi Xiong, Jing-Wen Wu, Yong-Chuan Li, Jia-Xin Xie, Hai-Ping Zhou, Guan-Yu Ye, Yuan Chang, Kai-Bin Huang, Su-Yue Pan
Published: 202610.1038/s41401-025-01706-4
Abstract
Cerebral edema is a severe complication following ischemic stroke. Recent studies have highlighted the crucial role of the glymphatic system (GS) in the clearance of water and macromolecules. GS dysfunction involving the disorders of AQP4 polarizatio…
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