Acta pharmacologica Sinica
Inhibiting L-type calcium channel promotes cardiomyocyte proliferation through activating the canonical Wnt signaling pathway.
Meng-Ying Feng, Yan-Song Tang, Su Yao, Hong-Jie Zhang, Bi-Lin Liu, Rong-Rong Huang, Shi-Qi Huang, Zhao-Hui Ou-Yang, Min Yuan, Rui Jiang, Da-Chun Xu, Guo-Hua Gong, Ke Wei
Published: 202610.1038/s41401-025-01704-6
Abstract
The adult human heart is incapable of regeneration after myocardial infarction (MI) injury. One potential therapeutic strategy is to enhance the proliferation of resident cardiomyocytes (CMs). In this study, we developed a high-content screening assa…
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