Pediatric research
Impact of mercaptopurine schedule on hypoglycemia in leukemic children: randomized trial and risk factor analysis.
Zhi-Yan Chen, Qiao-Ru Li, Liu-Hua Liao, Xiao-Ling Chen, Xiao-Lan Xiao, Hui Jin, Yu Li, Li-Na Wang, Cong Liang, Zhong Fan, Tian-Fang Yue, Cui-Yun Yang, Xue-Qun Luo, Yan-Lai Tang, Li-Bin Huang
Published: 202610.1038/s41390-025-04728-0
Abstract
BACKGROUND: Children with acute lymphoblastic leukemia (ALL) may develop hypoglycemia, potentially attributable to mercaptopurine (6-MP) during long-term maintenance chemotherapy. Since hypoglycemia is harmful to childhood neurodevelopment, it is nec…
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