OncogeneHumansProto-Oncogene Proteins c-aktEsophageal Squamous Cell CarcinomaLymphatic MetastasisAnimals
LAMP1 enhances DNA-PKcs-mediated AKT phosphorylation and VEGFC secretion to promote lymph node metastasis in esophageal squamous cell carcinoma.
Yikang Wang, Chang Yuan, Zhichao Liu, Ning Ma, Cong Qi, Boyao Yu, Haizhen Jin, Chenyang Tian, Chunguang Li, Zhigang Li
Published: 202610.1038/s41388-025-03664-x
Abstract
Lymph node metastasis (LNM) is a major determinant of poor prognosis in esophageal squamous cell carcinoma (ESCC), with patients remaining at high risk of postoperative recurrence in the absence of reliable predictors or effective interventions. To a…
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