Molecular psychiatry
Consistent decline of acetylcholine in microbiota-gut-brain axis mediates antibiotic-induced anxiety via regulating hippocampus microglial activation.
Ke Xu, Yi Ren, Shuang Zhao, Zhe Ren, Jiaolin Wang, Dianji Tu, Fei He, Jinzhou Feng, Wentao Wu, Qi Zhong, Jianjun Chen, Peng Xie
Published: 202510.1038/s41380-025-03431-0
Abstract
Antibiotics (AB) are widely abused in medicine and may be a risk factor for mental health. To better understand their effects, we observed mental disorder symptoms in AB-treated mice and patients, and investigated possible mechanisms. Using AB-treate…
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