Molecular psychiatryAnimalsAstrocytesRatsExtracellular VesiclesStress
A novel brain-to-gut communication pathway mediated by astrocyte-derived small extracellular vesicles modulates stress-induced intestinal inflammation.
Liliana Yantén-Fuentes, Matías Pizarro, Carolina Rojas, Carolina Pradenas, Maxs Méndez-Ruette, Katherine Corvalán, Gonzalo Bustos-Quevedo, Alejandro Luarte, Luis Federico Batiz, Patricia Luz-Crawford, Karina Pino-Lagos, Ursula Wyneken
Published: 202510.1038/s41380-025-03289-2
Abstract
The connection between stress-induced mood disorders and inflammatory bowel diseases (IBD) has been well-established. However, the cellular mechanisms by which psychological stress can influence intestinal inflammation remain mostly enigmatic. Here,…
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