Leukemia
Dynamics of clonal hematopoiesis and cellular responses to stress-induced toxicity in autologous stem cell transplantation.
Catarina M Stein, Raphael Hablesreiter, Friederike Christen, Pelle Löwe, Coral Fustero-Torre, Klara Kopp, Benjamin N Locher, Lena Nitsch, Robert Altwasser, Johanna Franziska Kerschbaum, Lars Bullinger, Leif S Ludwig, Paulina M Strzelecka, Frederik Damm
Published: 202510.1038/s41375-025-02823-z
Abstract
Autologous stem cell transplantation (ASCT) involves harvesting hematopoietic stem and progenitor cells (HSPCs) prior to chemotherapy and subsequent repopulation of the bone marrow. This process imposes a bottleneck, providing a framework to dissect…
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